At least three people were killed and several others injured on Tuesday when a train slammed into a charter bus in Biloxi, Mississippi, local TV station WLOX reported.
The accident happened at around 2 p.m. local time (3 p.m. ET).
More details to come. It was struck by an eastbound CSX train and pushed for about 300 feet down the tracks, city spokesman Vincent Creel was quoted by AP as saying.
Authorities said the bus was stopped on the tracks at the time, and witnesses told the Sun Herald the bus appeared to be stuck on the tracks.
The bus reportedly came from Austin, Texas.
A Biloxi police official is calling it a "terrible, chaotic scene", according to NBC News.
A nearby hospital set up a triage unit at the site to treat the injured, and helicopters were carrying the injured to hospitals that handle trauma cases.
Emergency crews were spotted removing people from the bus through the emergency windows.
The National Transportation Safety Board (NTSB) said it was aware of the crash and monitoring.