Three Sundays, including the final week of the season, will feature the Rams and Chargers playing early afternoon games at the same time - in a city that's already known for its consistently heavy traffic.
Newly appointed head coach Sean McVay and his staff provide instant reactions to each of their team's games.
The consecutive games will allow the Eagles to stay on the west coast rather than have to travel across the country three times this coming season.
The bye week, the annual trip to Dallas (Sunday Night Football, Nov. 19), the West Coast back-to-back, and a December 17 trip to visit the Giants mean that the Eagles will play at home only once between Nov. 5 vs. Denver and Christmas night.
This naturally has people already worrying about the logistics, considering the Los Angeles Memorial Coliseum is located just 12.3 miles away away from the StubHub Center - and both are located off the 110 freeway.
The league had as of Thursday morning started informing the Seahawks and the 31 other teams their schedules, which the NFL hammered out with a complex computer system and heavy consultation with its TV partners. Following the team's cross-country trip to Jacksonville, Los Angeles continues east to the United Kingdom to host the Arizona Cardinals at London's Twickenham Stadium as part of the NFL's International Series before heading into the bye week.
On Christmas Eve, the Rams visit the Tennessee Titans for the first time since 2009. The franchises last met in the regular season in 2015 at University of Minnesota's TCF Bank Stadium, a contest the Rams lost in overtime.
Then, the Rams head up to San Francisco for Week 3, followed by a trip to Dallas for Week 4.
The Lions traveled to practice with the Pittsburgh Steelers previous year prior to their preseason game.
All Rams games can be heard in English on ESPN LA 710 AM, with a full simulcast on 100.3 The Sound, and in Spanish on ESPN Deportes 1330AM.