They were identified as 77-year-old Robert Hogan, 48-year-old Jonell Boster and 17-year-old Carl Boster, all of Beech Grove, Indiana; and 59-year-old Lonnie Boster and 30-year-old Lonnie D. Boster, both of Indianapolis.
Police didn't release the identity of the sixth person, who was in a different passenger vehicle, pending notification of family. The passenger vehicle was stationary in the right lane of travel.
A juvenile passenger in the Hyundai ENT van has been admitted to Vanderbilt University Hospital for treatment of serious injuries sustained in the collision.
All lanes of I-65 northbound were closed at Exit 28 for hours but were reopened just after 5 a.m., according to Hodges and Joe Plunk, chief engineer for the Kentucky Transportation Cabinet in Bowling Green.
Traffic was congested due to the construction.
The Kentucky State Police accident reconstruction team will be working periodically this week at the site of the Thursday-night collision on northbound Interstate 65 that resulted in six deaths.
Police believe a northbound semi-truck struck a passenger vehicle which was stationary, causing a chain reaction collision involving one additional auto and semi. The collision involves two passenger vehicles and two commercial vehicles.
Hodges said the names of the dead haven't been released, and two haven't been identified. All northbound interstate traffic is being diverted onto USA 31W, near mile marker 28.