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A woman was gunned down by police in Florida after she crashed into a auto and then ran over a cop in her BMW along a busy stretch in South Beach, police and witnesses say.

"The auto was coming westbound from Ocean on 12th and went through the red light, struck an occupied vehicle on 12th and Collins", said Miami Beach Police Chief Dan Oates.

Cops in Florida killed a woman after an apparent hit-and-run crash where she knocked a police officer to the ground while trying to escape.

Miami-Dade police, an outside agency, will conduct the police shooting investigation.

Police Chief Daniel Oates said the incident started at about 6:15 p.m., when a woman driving a black BMW westbound on 12th Street hit a Mercedes with two men inside at Collins Avenue after running a red light.

Officers said the driver kept going and crashed into a white SUV on 12th Street and Collins Avenue. Both the driver and the officer were taken to the hospital. Police said another officer fired at the woman, who was struck by at least one round. He was in stable condition and alert late Sunday, Oates said. They said she was in her twenties. Emergency workers rushed her to Jackson Memorial Hospital, but she could not be saved.

A pair of tourists from Philly witnessed the initial crash from their dinner at the Sugar Factory patio along Ocean Drive.

Witnesses said the female driver backed up and tried to leave, despite pedestrians yelling at her to stop.

"She started the vehicle and ran away", said witness Miguel Garcia.

Garcia then said the woman was not breathing when she was pulled out of the vehicle and that there was blood everywhere.

Several people surrounded the driver, telling her to get out of the vehicle.