Going into the final qualifying fixture with third-placed Ireland, who are just a point behind Chris Coleman's side, Wales are on course for a play-off spot - if they are among the eight highest-ranked second-placed teams.
Wales are now second in Group D, with the Republic behind them by just one point.
- This victory means that Ireland ended the 2018 World Cup qualifiers unbeaten away from home (W3 D2 L0).
Aleksandar Prijovic scored after coming on as a second-half substitute to steer Serbia to a 1-0 win over Georgia and secure a place at next year's World Cup finals.
Coleman said: "We don't really talk about anything but what we need to be doing right now". The thinking is that as a result of the tune being stopped, the Red wall of supporters would create a lovely a cappella version of the song that would really get the player's up for the occasion.
Martin O'Neill (Republic of Ireland): "I think we can win the match".
Ireland now knew they just needed to see the game out while Wales, who knew a draw might be enough soon found out it would not as results elsewhere went against them.
"We changed the side to give us energy for a big game in Lille against Italy at the European Championships". Taylor's straight red for his tackle on Coleman in Wales' 0-0 draw with Ireland in March could, therefore, be said to be the difference. He has 26 goals in 68 worldwide appearances, including key strikes against Georgia and Serbia in the current campaign which should have put Wales on the road to Russian Federation. It was the first time Wales had fallen behind throughout the entire qualification campaign.
Wales's 1-0 win in Georgia formally put an end to the already very faint possibility that a draw would have sufficed on Monday.
"The job was to get the three points [against Moldova] no matter what and now we are fully focused and hopefully there will be a big crowd from Ireland".
"I just feel it is a wonderful night for soccer and it's a form of vindication for Martin O'Neill in particular".