The people who took ill came from IL (6), IN (11), MI (32), Missouri (10), and OH (1), the agency said.
WAVE3 reports here that the ISDH say 60 people in five states have been sickened as of June 7.
Walmart and Kroger are cooperating with the investigation and have removed all cut melon associated with the outbreak.
The products were sold at stores including Walmart, Walgreens, Costco and Kroger and other.
A recall has affected eight states, the CDC said.
Consumers with the recalled products are advised to throw them away or return them to the store for a refund.
A salmonella outbreak affecting five states including IL and Missouri is linked to pre-cut melons, according to IL health officials. It only applies to pre-cut melon and fruit salad mixes containing melon.
Individuals who have consumed pre-cut melon and are experiencing symptoms of Salmonella infection should contact a healthcare provider.
The IDPH says most people affected by Salmonella develop diarrhea, fever, and abdominal cramps 12 to 72 hours after eating food contaminated by the bacteria.
The CDC has indicated that pre-cut melon supplied by Caito Foods of Indianapolis is a likely source of the outbreak. For some people, though, the diarrhea that accompanies the illness may be severe and require hospitalization. The illness usually lasts four to seven days, and most people recover without treatment.
Meanwhile, in a separate scare not connected to the Caito Foods facility, the CDC said that a salmonella outbreak linked to backyard chickens made 124 people in 36 states sick.