They had the option of returning to Wembley, where they played all of their 2017-18 home games, or reversing all of their early home fixtures, but Mauricio Pochettino was wary of starting the season with a run of games on the road.
The Foxes are at home twice over the festive period with Premier League champions Manchester City to visit on Boxing Day, before promoted Cardiff City also head to King Power Stadium three days later.
Being the unbearably needy dweebs they are, the Premier League have chosen the first day of the World Cup to announce their fixtures for the 2018/19 season.
Promoted Fulham host Crystal Palace, while Cardiff visit Bournemouth.
Arsenal will begin proceedings by hosting the reigning champions at the Emirates before travelling to Stamford Bridge the following weekend. Oof.
"We are so excited to have the date of the first Premier League match at our new stadium", he said.
Tottenham will play their first game at their new stadium against Liverpool
The Champions League group stage will commence on 18-19 September, and last season's beaten finalists Liverpool face an away Premier League fixture before all of their six group games.
"Of course Cristiano from a physical point of view is a superman - he can be there in Qatar if he wants, but four more years at the highest level, to come back to the next World Cup, I feel it will be hard", said Mourinho of the Portugal striker, who turned 33 in February.
Guardiola will look to retain the Premier League title for the first time since Manchester United in 2008/09.
Spurs made the journey across north London to the national stadium last term while their successor ground to White Hart Lane was being built.
Both aiming for cup success and consistent finishes in the top four, the likes of Chelsea and Arsenal have been pushed down the league of late as the Reds and Spurs both climb.