A move to Everton had originally appeared to be in the cards, but Mina then emerged as a target for Manchester United as the Red Devils looked for an alternative to expensive targets Harry Maguire and Toby Alderweireld.
He has been at Spurs for three seasons and made 21 appearances last season.
The former Porto manager has voiced his frustration many times in pre-season about the Old Trafford outfit's inability to get deals over the line, with central midfielder Fred the only big name to arrive this summer. Mina's adviser, Felipe Russo, "angered" United by constantly demanding increased payments.
After negotiations now, there has been a breakthrough between the two clubs.
The paper claims that the Old Trafford outfit "are closing in on a £60m deal for Alderweireld" after the Londoners signalled they would be willing to lower their £75m asking price.
He enjoyed a stint at Southampton before sealing a move to Spurs in 2015.
With the player suffering an injury last term, Spurs boss Mauricio Pochettino turned to Jan Vertonghen and Davinson Sanchez as his preferred centre-back partnership. Jose could possibly line the player up alongside Eric Bailly for the 2018-19 season.
Alderweireld had an excellent World Cup campaign for Belgium and helped his side reach the semis.
The 83-time capped Belgium worldwide is expected to finalize his move to the Old Trafford in the next couple of days.