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The coalition said Wednesday's attack brought the tally of rebel missiles launched since 2015, the year it joined the Yemeni government's fight against the rebels, to 165.

That was the toll at just one hospital.

Yahya Shaem, head of the Houthi-held health office in Saada, told CNN that the children in the bus were on their way to their summer camps.

The Save the Children charity, quoting its staff, said that at the time of the attack the children were on a bus heading back to school "from a picnic when the driver stopped to get a drink".

"We are unable to verify the details at this moment", Save the Children wrote on August 9. But the coalition denied carrying out any attacks in the city, saying it follows a "strict and transparent approach based on the rules worldwide law".

"Scores killed, even more injured, most under the age of ten".

UNICEF Regional Director in the Middle East and North Africa Geert Cappelaere also responded to Thursday's strike, asking, "Does the world really need more innocent children's lives to stop the cruel war on children in Yemen?"

CBS News was witness to Yemen's war first hand in February as Saudi-backed soldiers were seen fighting against Houthi rebels for control of the country's barren hills.

"We are certainly concerned about the reports that there was an attack that resulted in the deaths of civilians".

The military alliance says it does not target civilians and has set up an investigation committee into alleged mass casualty air strikes which have mostly cleared the coalition of any blame.

State Department spokeswoman Heather Nauert said the USA was "concerned" by reports of an attack resulting in civilian deaths.

"Targeting Saudis and residents in Saudi is a red line", coalition spokesman Turki al-Malki later told Al Arabiya TV. US mid air support.

In a statement, Pentagon spokeswoman Rebecca Rebarich said that American aid helps reduce civilian casualties.

Later, air strikes were reported in the rebel-held Yemeni capital, Sanaa.

The Iran-aligned Houthis regularly fire into Saudi Arabia and have targeted its capital, Riyadh, with ballistic missiles.

In May, the Trump administration imposed sanctions on five Iranians linked with the Islamic Revolutionary Guard Corps (IRGC) who allegedly provided ballistic missile support to the Houthi rebels in Yemen which they then used to attack Saudi Arabia.

Nauert added the USA takes credible accounts of civilian casualties "very seriously".

Saada, the main stronghold of the Houthis, has mainly come under air strikes from the coalition as the mountainous province makes battles hard for pro-government ground troops.

It is with the stated aim of dislodging the Houthis, and restoring the previous government, that the Sunni coalition has waged a years-long airstrike campaign in the country with the support of the U.S. Since large-scale fighting erupted in 2015, the ensuing violence has left more than 10,000 people killed and the country's health infrastructure so badly battered, almost 18 million Yemenis lack reliable access to food.


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