Atalanta are without suspended Teun Koopmeiners but return Gianluca Scamacca for the visit to Lecce as they hope to lock down fifth place.
It kicks off at the Stadio Via del Mare at 17.00 UK time (16.00 GMT).
You can follow all the build-up and action as it happens from this game and Torino–Milan on the LIVEBLOG.
La Dea had been on sparkling form until losing the Coppa Italia Final 1-0 to Juventus on Wednesday.
Scamacca was suspended for that match and returns here, whereas Koopmeiners sits out a ban instead, with Marten de Roon, Sead Kolasinac and Emil Holm injured, so Giorgio Scalvini is moved into midfield.
The Coppa Italia was only the first in a crammed set of appointments this term, as Atalanta will face Bayer Leverkusen in the Europa League Final in Dublin on May 22.
They also want to lock down fifth place in Serie A and consequently Champions League qualification.
Lecce have already guaranteed top flight safety and will therefore be in the mood for celebration during their final home game of the season.
Roberto Piccoli returns from suspension, but Nicola Sansone, Lameck Banda, Mohamed Kaba and Kastriot Dermaku are injured.
Lecce vs. Atalanta line-ups
Lecce: Falcone; Gendrey, Baschirotto, Pongracic, Gallo; Berisha, Ramadani, Gonzalez; Piccoli, Krstovic, Dorgu
Atalanta: Musso; Toloi, Hien, Bonfanti; Hateboer, Scalvini, Pasalic, Zappacosta; Miranchuk; Scamacca, Toure
Player statistic
| 26' |  |
Hans Hateboer | ||
| 37' | |
El Bilal Touré | ||
| 44' | |
Mario Pasalic |
| 48' |  |
Charles De Ketelaere (Assist: Gianluca Scamacca) | ||
| 53' | |
Gianluca Scamacca (Assist: Aleksey Miranchuk) | ||
| 67' | |
Rafael Tolói |
